Pathway to Cures (P2C) is the National Bleeding Disorders Foundation’s venture philanthropy fund created specifically to accelerate the development of cures and therapies across all inheritable blood and bleeding disorders.

As a flexible partner working collaboratively with other organizations, P2C makes investments in innovative therapies, and technologies, leveraging the deep resources and scientific community relationships of the National Bleeding Disorders Foundation (NBDF). By reinvesting proceeds from investments back into the Fund, P2C will amplify our impact by supporting the progress of promising companies and building a deep and diverse portfolio of investments that further our mission.

Pathway to Cures Logo

Why Pathway to Cures?

While there has been significant progress made over the past decades on effective treatments for inheritable blood and bleeding disorders, that progress has been limited to hemophilia A and hemophilia B. The vast majority of inheritable blood and bleeding disorders have seen little progress made on development of disease modifying therapies, with a lack of funding for early-stage development being the biggest roadblock.

Leveraging our deep ties in the scientific community, P2C seeks to attract the additional capital needed from traditional venture capital, biotech and pharma entities to close the early-stage funding-gap and drive innovation in development of cures and treatments for those living with inheritable blood and bleeding disorders.

The Early Stage Funding Gap

Discovery &
Development
Pre-Clinical
Research
Clinical
Research
Federal
Review
Commercialization

Discovery & Development: Narrowing down thousands of potential targets to a handful, with researchers generating insights that help them identify new technologies or new uses for existing technologies.

Pre-Clinical Research: As research progresses, scientists work to further narrow the list of potential target molecules that show promise and work to further understand their mechanics.

Clinical Research: To help a developer understand the effects of a given biologic on humans, the drug candidate enters clinical trials on a small population of patients.

Government Review: The process of reviewing clinical data and chemistry, manufacturing, and controls information submitted to regulatory bodies takes time.

Commercialization: Pending FDA approval, the therapy or technology enters into the market for widespread use.

Relationship with the National Bleeding Disorders Foundation (NBDF)

P2C is a catalyst in realizing NBDF’s vision of a world without inheritable blood and bleeding disorders.

With NBDF as its parent organization, P2C provides the competitive advantage of expertise in inheritable blood and bleeding disorders research with deep ties to the advocacy and broader scientific communities. Leveraging NBDF resources, P2C can invest in innovative therapies and technologies while “de-risking” the investments for our private capital partners by providing in-depth access to a network of leading scientific research and experts.

NBDF is a donor to P2C and a critical partner in realizing our mission. However, P2C operates independently, and is run by an experienced team of investors, scientific researchers, and medical and healthcare professionals.

A Message
to Donors

The National Bleeding Disorders Foundation’s Pathway to Cures is registered as a non-profit with 501(c)(3) status. As a venture philanthropy fund, neither management nor donors to P2C will receive capital distributions.

This is the opportunity to become a founding member of a truly unique and innovative organization. P2C offers a significant opportunity for donors who want to make a transformative impact on the development of treatments and cures across all inheritable blood and bleeding disorders.

To maximize impact and accelerate the growth of our portfolio, P2C is asking for minimum donations of $500,000. P2C will accept donations from individuals, groups, and institutions. If you are interested in learning more about donating or partnering with P2C, please get in touch by filling out the form below. We look forward to connecting with you and discussing this exciting opportunity.

Let’s Find Cures Together!

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